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Oscillating Formation of 8-Oxoguanine during DNA Oxidation

✍ Scribed by White, Blánaid; Smyth, Malcolm R.; Stuart, James D.; Rusling, James F.

Book ID
126472114
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
41 KB
Volume
125
Category
Article
ISSN
0002-7863

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Electrochemical Oxidation of 8-Oxoguanin
Electrochemical Oxidation of 8-Oxoguanine
✍ A. M. Oliveira Brett; J. A. P. Piedade; S. H. P. Serrano 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 169 KB 👁 1 views

Electrochemical oxidation of DNA can occur at each of the four bases and guanine is the one that can suffer the easiest oxidative damage. The occurrence of the guanine oxidation product, 8-oxoguanine, as a consequence of DNA damage caused by DNA oxidation causes important mutagenic lesions and hence