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Orthodontic effects of bisphosphonates

Book ID: 116403065
Publisher: Elsevier Science
Year: 2010
Weight: 272 KB
Volume: 55
Category: Article
ISSN: 0011-8486
DOI: 10.1016/j.denabs.2010.06.009

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## Background: Bisphosphonates are widely used to treat skeletal complications of malignancy. these drugs accumulate in bone where they inhibit osteoclastic bone resorption and reduce the local release of factors that stimulate tumor growth. the mechanism of action of bisphosphonates is dependent o