The synthesis of new 3-substituted a-carbolines is described and these products were subjected to ortho-lithiation experiments. 3-pivalamido and 3-carboxamido derivatives are cleanly lithiated at 4position. The results are correlated with MNDO calculations. Various 3,4-disubstituted a-carbolines are
โฆ LIBER โฆ
Ortho-directed lithiation studies of 3-carboxy-.beta.-carbolines: a direct route to 4-substituted derivatives
โ Scribed by Mehta, Anita; Dodd, Robert H.
- Book ID
- 126797563
- Publisher
- American Chemical Society
- Year
- 1993
- Tongue
- English
- Weight
- 551 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0022-3263
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