ortho-(Aminomethyl)phenylboronic acids—synthesis, structure and sugar receptor activity
✍ Scribed by Agnieszka Adamczyk-Woźniak; Zbigniew Brzózka; Michał K. Cyrański; Alicja Filipowicz-Szymańska; Paulina Klimentowska; Anna Żubrowska; Kamil Żukowski; Andrzej Sporzyński
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 326 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0268-2605
- DOI
- 10.1002/aoc.1418
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✦ Synopsis
Abstract
A series of ortho‐(aminomethyl)phenylboronic acids was synthesized and their structures were determined by single‐crystal X‐ray diffraction. The structures are stabilized by the inter‐ and intramolecular hydrogen bonds. The sugar‐binding ability of these compounds was evaluated for D‐glucose, D‐fructose and D‐galactose by the competition assay with Alizarin Red S (ARS). The results indicate that the sugar binding ability and selectivity towards sugars depend on the substituents in amino group. Copyright © 2008 John Wiley & Sons, Ltd.