Orphanin FQ/nociceptin attenuates the development of morphine tolerance in rats
β Scribed by Kabirullah Lutfy; Syed M Hossain; Imran Khaliq; Nigel T Maidment
- Book ID
- 110005886
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 207 KB
- Volume
- 134
- Category
- Article
- ISSN
- 0007-1188
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π SIMILAR VOLUMES
The endogenous ligand for the orphan opioid receptor, orphanin FQ/nociceptin (OFQ), has recently been characterized. The OFQ peptide sequence contains paired basic amino acids, suggesting the possibility of posttranslational processing to a peptide containing the first 11 amino acids of the OFQ pept
## Abstract In the central nervous system, glial cells play an important role in inflammatory and immune responses, and opioid peptides have been identified as essential mediators between the nervous and the immune systems. We report the profound upregulation of the opioidβrelated nociceptin/orphan