โ Scribed by Jean-Paul Goulet, Ana Miriam Velly (eds.)
No coin nor oath required. For personal study only.
This book provides up-to-date information on all aspects of orofacial pain biomarkers. It opens by presenting background information on clinical phenotypes and the neurobiological substrates underlying chronic orofacial pain and by explaining the potential role of biomarkers in the diagnosis, prognostic evaluation, and treatment of orofacial pain. The main section of the book examines the contribution of human and animal studies to the field of biomarkers for orofacial pain and discusses biomarkers for masticatory muscle pain, temporomandibular joint pain, neuropathic face pain, and autonomic nervous system involvement in trigeminal facial pain. The potential impacts of the immune system on orofacial pain biomarkers and candidate gene phenotypes with possible links to chronic orofacial pain conditions are also addressed, and differences and similarities between saliva and serum biomarkers for pain are explained as well. The final section covers research-related issues in assessment methods and statistical analyses used in evaluating biomarkers, identifies future challenges and suggests new directions in the field.
Front Matter....Pages i-x
Front Matter....Pages 1-1
Orofacial Pain: Classification and Road Map to Clinical Phenotypes....Pages 3-20
Comorbidities in Individuals with Orofacial Pain and Their Impact on Biomarkers....Pages 21-32
Front Matter....Pages 33-33
Neurobiological Mechanisms of Chronic Orofacial Pain....Pages 35-46
Oral and Craniofacial Pain: Contribution of Endogenous, Central Modulation Mechanisms....Pages 47-61
Front Matter....Pages 63-63
Neurophysiologic Markers of Neuropathic Orofacial Pain....Pages 65-77
Masticatory Muscle Pain Biomarkers....Pages 79-93
Molecular Temporomandibular Joint Pain Biomarkers....Pages 95-105
Genetic Biomarkers of Orofacial Pain Disorders....Pages 107-118
Serum, Synovial, and Salivary Biomarkers for Orofacial Pain Conditions....Pages 119-131
Front Matter....Pages 133-133
Biomarkers in Epidemiologic Research: Definition, Classification, and Implication....Pages 135-139
Statistical Analysis in the Identification of Pain Biomarkers....Pages 141-145
Future Direction and Conclusion....Pages 147-150
Back Matter....Pages 151-155
Dentistry;Oral and Maxillofacial Surgery;Pain Medicine
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