Ornithine Decarboxylase from Mouse Epidermis and Epidermal Papillomas: Differences in Enzymatic Properties and Structure

The tumor promoter 12-0-tetradecanoylpho

The tumor promoter 12-0-tetradecanoylphorbol-13-acetate induces ornithine decarboxylase in proliferating basal cells but not in differentiating cells from mouse epidermis

✍ Ulrike Lichti; Elroy Patterson; Henry Hennings; Stuart H. Yuspa 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 842 KB

## Abstract The cultivation of mouse epidermal cells in medium of reduced calcium concentration (0.02–0.1 mM) selects for basal cell growth. Elevation of medium calcium levels above 0.1 mM results in rapid and well defined differentiative changes. This model was utilized to determine which cell typ