Ornithine decarboxylase as a tool in developmental neurobiology
โ Scribed by Theodore A. Slotkin
- Book ID
- 118939050
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 390 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0024-3205
No coin nor oath required. For personal study only.
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I-Ornithine decarboxylase (ODC) is essential for polyamine synthesis and growth in mammalian cells; it provides putrescine that is usually converted into the higher polyamines, spermidine and spermine. Many highly specific and potent inhibitors of ODC are based on the lead compound a-difluoromethylo
## Ornithine decarboxylase as a marker for colorectal adenomas Sir I was interested to read the paper by Moorehead and colleagues (Br J Surg 1987; 74: 3645). In their discussion the authors state that the finding of diminished levels of ornithine decarboxylase in macroscopically normal rectal muco