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Origin of β-Hairpin Stability in Solution: Structural and Thermodynamic Analysis of the Folding of a Model Peptide Supports Hydrophobic Stabilization in Water

✍ Scribed by Maynard, Allister J.; Sharman, Gary J.; Searle, Mark S.


Book ID
126271823
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
203 KB
Volume
120
Category
Article
ISSN
0002-7863

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## Abstract The structural properties of a 10‐residue and a 15‐residue peptide in aqueous solution were investigated by molecular dynamics simulation. The two designed peptides, SYINSDGTWT and SESYINSDGTWTVTE, had been studied previously by NMR at 278 K and the resulting model structures were class