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Origin of the Spinocerebellar Ataxia Type 7 Gene Mutation in Mexican Population

✍ Scribed by J. J. Magaña, R. Gómez, M. Maldonado-Rodríguez, L. Velázquez-Pérez…


Book ID
120960364
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
230 KB
Volume
12
Category
Article
ISSN
1473-4222

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✍ Elisa Alonso; Leticia Martínez-Ruano; Irene De Biase; Christopher Mader; Adriana 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 77 KB

## Abstract Dominant ataxias show wide geographic variation. We analyzed 108 dominant families and 123 sporadic ataxia patients from Mexico for mutations causing SCA1–3, 6–8, 10, 12, 17 and DRPLA. Only 18.5% of dominant families remained undiagnosed; SCA2 accounted for half (45.4%), followed by SCA