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Origin of the Enantioselectivity in the Hydrogen Transfer Reduction of Carbonyls by a Rhodium(I) Complex: A Theoretical Study

✍ Scribed by Guiral, Vincent; Delbecq, Françoise; Sautet, Philippe


Book ID
127057844
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
187 KB
Volume
20
Category
Article
ISSN
0276-7333

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## Abstract Amino acid based thioamides, hydroxamic acids, and hydrazides have been evaluated as ligands in the rhodium‐catalyzed asymmetric transfer hydrogenation of ketones in 2‐propanol. Catalysts containing thioamide ligands derived from L‐valine were found to selectively generate the product w