## Abstract One of the seminal events in the history of neurology was the identification of primary diseases of muscle and their separation from diseases in which muscle weakness was secondary to injury involving the anterior horns of the spinal cord (βprogressive muscular atrophyβ). Not surprising
Origin of new mutations in Duchenne muscular dystrophy
β Scribed by Laura Roncuzzi; Alessandra Ferlini; Adriana Pirozzi; G. Romeo
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 300 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0340-6717
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The letter by on the theoretical expectations for deletional mutations in Duchenne muscular dystrophy (DMD) is very misleading. The authors base al1 of their arguments and calculations on the hypothesis that, in DMD, deletions occur exclusively or aimost exclusively by homologous recombination, and
Motor neuron abnormalities have been implicated in the pathogenesis of Duchenne muscular dystrophy. Evidence concerning the effect of injury on motor neurons of human Duchenne muscular dystrophy (DMD) is lacking. We report a DMD patient having, in addition, an obstetric paresis on his left arm. EMG
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