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Origin of Developmental Precursors Dictates the Pathophysiologic Role of Cardiac Fibroblasts

โœ Scribed by Jeffrey R. Crawford, Sandra B. Haudek, Katarzyna A. Cieslik, JoAnn Trial, Mark L. Entman

Book ID
118824956
Publisher
Springer US
Year
2012
Tongue
English
Weight
771 KB
Volume
5
Category
Article
ISSN
1937-5387

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## Abstract Fibroblasts are at the heart of cardiac function and are the principal determinants of cardiac fibrosis. Nevertheless, cardiac fibroblasts remain poorly characterized in molecular terms. Evidence is evolving that the cardiac fibroblast is a highly heterogenic cell population, and that s