Origin of anti-tumor immunity failure in mammals and new possibility for immunotherapy
β Scribed by I.V Bubanovic
- Book ID
- 117494443
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 119 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0306-9877
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The adoptive transfer of tumor-specific transplantation immunity was accomplished in a syngeneic rat tumor-host system. Rats which received intravenous injections of spleen cells from Fisher 344/N rats immunized by amputation of growing isografts of a benz(a)pyrene-induced fibrosarcoma (BP-1R) manif
## Abstract A patient with melanoma was found to have lymphocytes highly cytotoxic for autogenous tumor cells but not for fibroblasts. Autogenous serum did not block the cytotoxicity. He then received an injection of BCG into a small tumor nodule. Three weeks later, in association with accelerated