✦ LIBER ✦

Origin, maturation and antigen presenting function of dendritic cells

✍ Scribed by Marina Cella; Federica Sallusto; Antonio Lanzavecchia

Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 641 KB
Volume: 9
Category: Article
ISSN: 0952-7915
DOI: 10.1016/s0952-7915(97)80153-7

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✦ Synopsis

Dendritic cells are cells specialized for antigen capture, migration and T cell stimulation. Recent advances have been made in understanding their origin, their heterogeneity, the mechanism of antigen uptake, and the signals that induce their migration and maturation into immunostimulatory antigen-presenting cells. Dendritic cells represent the natural adjuvants for T cell responses and their therapeutic exploitation in the near future is foreseen.

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