The prognostic values of loss of heterozygosity (LOH) at loci frequently involved in non-small cell lung cancer and of KRAS2 gene mutations were studied in lung adenocarcinoma patients. LOHs were relatively common, ranging from 24% at chromosome 10p to 55% at chromosome 17p13. KRAS2 mutations at cod
β¦ LIBER β¦
Origin and prognostic value of circulating KRAS mutations in lung cancer patients
β Scribed by O. Gautschi; B. Huegli; A. Ziegler; M. Gugger; J. Heighway; D. Ratschiller; P.C. Mack; P.H. Gumerlock; H.J. Kung; R.A. Stahel; D.R. Gandara; D.C. Betticher
- Book ID
- 116334433
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 491 KB
- Volume
- 254
- Category
- Article
- ISSN
- 0304-3835
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## Abstract This study was conducted to evaluate the significance of circulating free DNA (CFDNA), p53 antibody (p53βAb) and mutations of __KRAS__ gene in the development of endometrial cancer (EC). A total of 109 patients with EC (87 patients with Type I and 22 patients with Type II) took part in