Organs as targets of “dioxin” (2,3,7,8-tetrachlorodibenzo-p-dioxin) intoxication
✍ Scribed by N. P. Buu-Hoï; Pham-Huu Chanh; G. Sesqué; M. C. Azum-Gelade; G. Saint-Ruf
- Publisher
- Springer
- Year
- 1972
- Tongue
- English
- Weight
- 587 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0028-1042
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## Abstract The contaminant 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin (TCDD) is a prototype compound of a whole class of halogenated aromatic hydrocarbons termed ‘dioxinlike’ contaminants present in food, human tissue, mothers milk, and environmental samples. Among the various adverse effects caused
Concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rat liver and adipose tissue, and hepatic ethoxyresorufin O-deethylase (EROD) activity were studied subsequent to a single subcutaneous injection of TCDD. Two types of experiments were performed to study: (a) time-dependent changes foll