Organotin(IV) esters of (E)-3-furanyl-2-phenyl-2-propenoic acid: Synthesis, investigation of the coordination modes by IR, multinuclear NMR (1H, 13C, 119Sn) and In Vitro biological studies

✍ Scribed by Sadiq-ur-Rehman; Saqib Ali; Saira Shahzadi

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 130 KB
• Volume: 19
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20488

✦ Synopsis

Complexes [Me 2 SnL 2 (I), Me 3 SnL (II),

Et 2 SnL 2 (III), n-Bu 2 SnL 2 (IV), n-Bu 3 SnL (V), n-Oct 2 SnL 2 (VI)], where L is (E)-3-furanyl-2-phenyl-2propenoate, have been synthesized and structurally characterized by vibrational and NMR ( 1 H, 13 C and 119 Sn) spectroscopic techniques in combination with mass spectrometric and elemental analyses. The IR data indicate that in both the di-and triorganotin(IV) carboxylates the ligand moiety COO acts as a bidentate group in the solid state. The 119 Sn NMR spectroscopic data, 1 J [ 119 Sn, 13 C] and 2 J [ 119 Sn, 1 H], coupling constants show a four-coordinated environment around the tin atom in triorganotin(IV) and fivecoordinated in diorganotin(IV) carboxylates in noncoordinating solvents. The complexes have been screened against bacteria, fungi, and brine-shrimp larvae to assess their biological activity.