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Organophosphorus compound esterase profiles as predictors of therapeutic and toxic effects

✍ Scribed by Makhaeva, Galina F.; Radchenko, Eugene V.; Palyulin, Vladimir A.; Rudakova, Elena V.; Aksinenko, Alexey Yu.; Sokolov, Vladimir B.; Zefirov, Nikolay S.; Richardson, Rudy J.


Book ID
119999874
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
572 KB
Volume
203
Category
Article
ISSN
0009-2797

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## Abstract Knowledge of partition coefficient (log __P__) data can play a critical role in understanding the pharmacokinetic and pharmacodistributive properties of toxic organophosphorus (OP) compounds. Using a recently published gas chromatographic method, the octanol:water log __P__ values for t