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Organomanganese (II) reagents XVI1: copper-catalyzed 1,4-addition of organomanganese chlorides to conjugated enones

✍ Scribed by Gérard Cahiez; Mouad Alami

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
258 KB
Volume
30
Category
Article
ISSN
0040-4039

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✦ Synopsis

conjugate addition reaction efficiently and the butyl manganese chloride could be indifferently prepared from butyllithium or butyhnagnesium halide.

As shown in Table I and II, the scope of this reaction is very broad. Thus, high yields of 1,4-addition products were obtained from a vast array of cyclic or acyclic conjugated enones (Table I). Even the p,p-bisubstituted o$-ethylenic ketones, which are well known to undergo the conjugate addition of an organocopper or an organocuprate reagent with difficulty, react easily and cleanly under our conditions (enfries 7 ro II).

📜 SIMILAR VOLUMES

Organomanganese (II) reagents XXII. Copp
Organomanganese (II) reagents XXII. Copper-catalyzed conjugate addition of organomanganese reagents to α, β-ethylenic esters.
✍ Gérard Cahiez; Mouad Alami 📂 Article 📅 1990 🏛 Elsevier Science 🌐 French ⚖ 136 KB

## Copper-catalyzed conjugate addition of organomanganese reagents to a, B ethylenic esters easily takes place in THF at O'C, in the presence of 3% CuCl and MejSiCI. Good to moderate yields are obtained from organomanganese reagents preparedfrom organolithium or organomagnesium compounok Recently,