Organomanganese (II) reagents XIX. Acylation of organomanganese chlorides by carboxylic acid chlorides in THF: A clear improvement in the field of the preparation of ketones from organomanganese compounds
✍ Scribed by Gérard Cahiez; Blandine Laboue
- Book ID
- 104212357
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 265 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Organomanganese chloride reagents reuct with carboxylic acid chlorides, in THF, to give the corresponding ketones in excellent yields. The reaction is of broad scope, it is very interesting from practical and economical point of view since organomanganese chlorides (in THF) are the most stable and cheap organomanganese reagents. With methyl, aryl, aikenyl and s-or r-alkylmanganese chlorides, the acylation is advantageously performed in the presence of a catalytic amount of copper chloride. This new procedure allows to prepare methyl, aryl and alkenylketones as well as s-or t-ulkylketones in good yields.