Organoiodine (III) Mediated Synthesis of 3-Aryl/Hetaryl-5,7-dimethyl-1,2,4-triazolo[4,3-a]pyrimidines as Antibacterial Agents.
β Scribed by Om Prakash; Vikas Bhardwaj; Ravi Kumar; Parikshit Tyagi; Kamal R. Aneja
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 16 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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## Abstract Oxidation of bisβ2,4βpyrimidinylhydrazones of various araldehydes with two equivalents of iodobenzene diacetate in dichloromethane provides an efficient and easy method for the synthesis of eight new 3,9βdiarylβbisβ1,2,4βtriazolo[4,3β__a__][4,3β__c__]pyrimidines. Β© 2006 Wiley Periodical
## Abstract Starting from pyrimido[4,5βe][1,3,4]oxadiazines **(****3a**, **3b**, **3c****)**, a synthetic pathway to [1,2,4]triazolo[4β²,3β²:1,2]pyrimido[4,5βe][1,3,4]oxadiazines **(****5a**, **5b**, **5c**, **5d**, **5e**, **5f**, **5g**, **5h**, **5i****)** is described. The reaction of pyrimido[4,