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Organocatalytic Michael Addition, a Convenient Tool in Total Synthesis. First Asymmetric Synthesis of (-)-Botryodiplodin.

โœ Scribed by Olivier Andrey; Annick Vidonne; Alexandre Alexakis


Book ID
101955173
Publisher
John Wiley and Sons
Year
2004
Weight
57 KB
Volume
35
Category
Article
ISSN
0931-7597

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Chromans form the core of numerous natural products and synthetic analogues displaying a broad and interesting range of biological activities. [1] In particular, the chiral chroman skeleton plays an important role in various therapeutic areas. [1d] For example, (ร€)-siccanin, isolated from the cultur