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Organocatalytic Highly Enantioselective Michael Addition of 2-Hydroxy-1,4-naphthoquinones to Nitroalkenes

✍ Scribed by Zhou, Wen-Ming; Liu, Han; Du, Da-Ming


Book ID
120831636
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
413 KB
Volume
10
Category
Article
ISSN
1523-7060

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Highly Enantioselective Organocatalytic
✍ Yi-Feng Wang; Wei Zhang; Shu-Ping Luo; Guang-Cun Zhang; Ai-Bao Xia; Xiang-Sheng 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB 👁 1 views

## Abstract An organocatalytic enantioselective Michael addition of 2‐hydroxy‐1,4‐naphthoquinone to β,γ‐unsaturated α‐oxo esters has been developed. The process was promoted by bifunctional chiral amine derived squaramides according to a hydrogen‐bonding mediated activation mechanism and afforded t