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Organocatalytic enantioselective tandem aldol-cyclization reaction of α-isothiocyanato imides and activated carbonyl compounds

✍ Scribed by Jie Guang; Cong-Gui Zhao


Book ID
113929503
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
535 KB
Volume
22
Category
Article
ISSN
0957-4166

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✍ Martín J. Riveira; Dr. Mirta P. Mischne 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 362 KB

## Abstract A new cascade pathway viable for Knoevenagel chemistry that involves the coupling between 1,3‐dicarbonyl systems and α,β,γ,δ‐unsaturated aldehydes has been developed. The process comprises the combination of a classic aldol‐type condensation and a rare spontaneous metal‐free cycloisomer