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Organocatalytic Asymmetric Direct CH Functionalization of Ethers: A Highly Efficient Approach to Chiral Spiroethers

✍ Scribed by Zhi-Wei Jiao; Dr. Shu-Yu Zhang; Prof. Chuan He; Prof. Yong-Qiang Tu; Prof. Shao-Hua Wang; Prof. Fu-Min Zhang; Dr. Yong-Qiang Zhang; Hui Li


Book ID
112001395
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
726 KB
Volume
51
Category
Article
ISSN
0044-8249

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First catalytic asymmetric hydrophosphon
✍ Harald GrΓΆger; Yoshinobu Saida; Shigeru Arai; JΓΌrgen Martens; Hiroaki Sasai; Mas πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 French βš– 160 KB

The catalytic and enantioseleetive hydrophosphonylation of a cyclic imine, namely the 3thiazoline I, is described. We have discovered a highly efficient enantioselective de novo approach to the pharmaceutically interesting 4-thiazolidinylphosphonate 2 using either titanium or lanthanoid chiral catal