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Organocatalytic anti-Mannich Reactions with Dihydroxyacetone and Acyclic Dihydroxyacetone Derivatives: A Facile Route to Amino Sugars

✍ Scribed by Haile Zhang; S. S. V. Ramasastry; Fujie Tanaka; Carlos F. Barbas III


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
227 KB
Volume
350
Category
Article
ISSN
1615-4150

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✦ Synopsis


Abstract

The first primary amine‐containing amino acid‐catalyzed anti‐Mannich reactions of dihydroxyacetone and acyclic dihydroxyacetone derivatives with a variety of imines have been developed. This approach complements proline‐based strategies in the preparation of amino sugars.