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Organocatalysts Promote Enantioselective 1,3-Dipolar Cycloadditions of Nitrones with 1-Cycloalkene-1-carboxaldehydes.

✍ Scribed by Staffan Karlsson; Hans-Erik Hoegberg


Publisher
John Wiley and Sons
Year
2003
Weight
182 KB
Volume
34
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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Organocatalysts Promote Enantioselective
✍ Staffan Karlsson; Hans-Erik HΓΆgberg πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 209 KB

## Abstract In the presence of enantiopure organocatalysts, 1‐cycloalkene‐1‐carboxaldehydes and various nitrones furnished fused isoxazolidines. Thus, some chiral pyrrolidinium salts catalyzed the formation of such cycloadducts in high diastereo‐ and enantioselectivity (up to 92% __ee__). The predo