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Organization and expression of the human zo-2 gene (tjp-2) in normal and neoplastic tissues

✍ Scribed by Alexandre Chlenski; Kathleen V Ketels; Galina I Korovaitseva; Mark S Talamonti; Ryoichi Oyasu; Dante G Scarpelli

Book ID
114147184
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
351 KB
Volume
1493
Category
Article
ISSN
0167-4781

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✍ Alexandre Chlenski; Kathleen V. Ketels; J. Luke Engeriser; Mark S. Talamonti; Mi πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 374 KB πŸ‘ 1 views

We have observed that 2 forms of zonula occludens 2 (ZO-2) protein, ZO-2A and ZO-2C, are expressed in normal human pancreatic duct cells, but only ZO-2C in pancreatic duct adenocarcinoma. We report here partial organization of the zo-2 gene. Transcription of 2 forms of ZO-2 mRNA is driven by alterna