Organic/Inorganic bioactive materials Part III: in vitro bioactivity of gelatin/silicocarnotite hybrids

✍ Scribed by Radev, Lachezar ;Fernandes, Maria ;Salvado, Isabel ;Kovacheva, Daniela

• Book ID: 111488092
• Publisher: Walter de Gruyter GmbH
• Year: 2009
• Tongue: English
• Weight: 689 KB
• Volume: 7
• Category: Article
• ISSN: 2391-5420
• DOI: 10.2478/s11532-009-0078-z

✦ Synopsis

In this work we present our experimental results on synthesis, structure evolution and in vitro bioactivity assessment of new gelatin/ silicocarnotite hybrid materials. The hybrids were obtained by diluting gelatin (G) and silicocarnotite (S) ceramic powder with G:S ratios of 75:25 and 25:75 wt.% in hot (40 o C) water. The hybrids were characterized using XRD, FTIR, SEM/EDS and XPS. FTIR depicts that the "red shift" of amide I and COO -could be attributed to the fact that the gelatin prefers to chelate Ca 2+ from S. The growth of calcium phosphates on the surface of the hybrids synthesized and then immersed in 1.5 SBF for 3 days was studied by using of FTIR, XRD and SEM/EDS. According to FTIR results, after an immersion of 3 days, A and B-type CO 3 HA can be observed on the surface. XRD results indicate the presence of hydroxyapatite with well defined crystallinity. SEM/EDS of the precipitated layers show the presence of CO 3 HA and amorphous calcium phosphate on the surface of samples with different G/S content when immersed in 1.5 SBF. XPS of the G/S hybrid with 25:75 wt.% proved the presence of Ca-deficient hydroxyapatite after an in vitro test for 3 days.