Organic synthesis using haloboration reaction, II. A stereo- and regioselective synthesis of [Z]-1-Alkynyl-2-halo-1-alkenes
β Scribed by Shoji Hara; Yoshitaka Satoh; Hiroko Ishiguro; Akira Suzuki
- Book ID
- 108381842
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 178 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
The cross-coupling reaction of orqanozinc chlorides with (Z)-2bromo-1-alkenylboranes prepared by the bromoboration reaction of 1-alkynes with tribromoborane, proceeds in the presence of a palladium catalyst to give 2,2\_disubstituted alkenylboranes, which can be used for the di-or trisubstituted alk
1-Alkenyldibromoboranes readily obtainable by the hydroboration of first alkyneswith dibromoborane-dimethyl sulfide followed by treatment with tribromoborane, react without any difficulty with second 1-alkynes as bromoborating agents to give (l-alkenyl)(Z-bromo-l-alkeny)bromoboranes (5). The reactio
## Abstract magnified image Described herein is the development of a palladium(II)βcatalyzed twoβ or threeβcomponent reaction of 2β(1βalkynyl)β2βalkenβ1βones with nucleophiles and allylic chlorides. Various types of nucleophiles such as __Oβ__, __Nβ__, __C__βbased nucleophiles and olefinβtethered