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Organic synthesis: The Wittig reaction cleans up

✍ Scribed by Marsden, Stephen P.


Book ID
109912890
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
179 KB
Volume
1
Category
Article
ISSN
1755-4330

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Horner-Wittig reaction aldehydes can be converted into their homologous ensmines by with ?&morpholinomethyl diphenylphosphine oxide (2. Among the various methods that are used for the homologation of csrbonyl compounds, Wittig and Horner-Wittlg reactions with a-heterosubstituted ylides occupy a pro

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## Abstract A simple synthesis of a series of bicyclo[m.n.0]‐1‐alkenes (m, n = 3,4,5) from 2‐oxocycloalkanecarboxylates by the intramolecular __Wittig__ reaction is reported (see p. 70–72). The spectral properties (IR., ^1^H‐NMR. and ^13^C‐NMR.) of these annulated trisubstituted olefins are discuss