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Organic Synthesis (State of the Art 2003-2005) || New Routes to Heterocycles

โœ Scribed by Taber, Douglass F.

Publisher
John Wiley & Sons, Inc.
Year
2006
Tongue
English
Weight
757 KB
Edition
1
Category
Article
ISBN
0470053313

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โœฆ Synopsis

The efficient construction of substituted heterocycles is central to medicinal chemistry. Yoshinori Kondo of Tohoku University reports (J. Am. Chem. SOC. 125: 8082,2003) that the novel base 2 will, in the presence of Zn12 and an aldehyde, deprotonate heterocycles, to give the hydroxyalkylated products 3 and 5. Benzene rings also participate -6 is converted to 7.

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