✦ LIBER ✦

Organic synthesis planning: a new algorithm for strategic bond perception

✍ Scribed by Luca Baumer; Giordano Sala; Guido Sello

Publisher: Elsevier Science
Year: 1988
Tongue: French
Weight: 603 KB
Volume: 44
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(01)85899-3

No coin nor oath required. For personal study only.

✦ Synopsis

A new algorithm which generates breaking suggestion for Organic Synthesis Planning (OSP) is described.

A new strategical approach to organic synthesis design has been used. New definition for structural complexity weight, atom complexity distance, molecular centre, Minimal Sets of Strategic Bonds are presented.

The need for separate program sections for the strategic part and the transformation model is addressed. Some results are given and comments made to illustrate the algo_ rithm performance.

📜 SIMILAR VOLUMES

Ring perception in organic structures: A

Ring perception in organic structures: A new algorithm for finding SSSR

✍ Luca Baumer; Giordano Sala; Guido Sello 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 482 KB

New Strategic Reactions for Organic Synt

New Strategic Reactions for Organic Synthesis: Catalytic Asymmetric C—H Activation α to Nitrogen as a Surrogate for the Mannich Reaction.

✍ Huw M. L. Davies; Chandrasekar Venkataramani; Tore Hansen; Darrin W. Hopper 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 320 KB 👁 2 views

New Strategic Reactions for Organic Synt

New Strategic Reactions for Organic Synthesis: Catalytic Asymmetric C—H Activation α to Oxygen as a Surrogate to the Aldol Reaction.

✍ Huw M. L. Davies; Rohan E. J. Beckwith; Evan G. Antoulinakis; Qihui Jin 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 290 KB 👁 2 views

Chiral Nonracemic Late-Transition-Metal

Chiral Nonracemic Late-Transition-Metal Organometallics with a Metal-Bonded Stereogenic Carbon Atom: Development of New Tools for Asymmetric Organic Synthesis

✍ Helena C. Malinakova 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 391 KB 👁 1 views

## Abstract Transition‐metal‐catalyzed cross‐coupling reactions and the Heck reaction have evolved into powerful tools for the construction of carbon–carbon bonds. In most cases, the reactive organometallic intermediates feature a carbon–transition‐metal σ bond between a sp^2^‐hybridized carbon ato

ChemInform Abstract: Cyclopropyl Buildin

ChemInform Abstract: Cyclopropyl Building Blocks for Organic Synthesis. Part 63. Palladium-Catalyzed Additions of Silyl-Element Bonds to Bicyclopropylidene — A New Access to Bicyclopropyl and Functionally Substituted Cyclopropylidenepropane Derivatives.

✍ Tim Pohlmann; Armin de Meijere 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views