Organic Structure Determination Using 2-D NMR Spectroscopy. A Problem-Based Approach

✍ Scribed by Jeffrey H. Simpson (Auth.)

• Publisher: Academic Press
• Year: 2012
• Tongue: English
• Leaves: 573
• Edition: 2
• Category: Library

✦ Synopsis

This book contains 60 quality 2D NMR data sets following an introductory section describing the methodology employed. Many other books describe the methods used, but none offer a large number of problems. Instructors at universities and colleges at the present time are forced to cobble together problems from a wide range of sources. The fragmentary approach to assembling course materials has a negative impact on course continuity and thus adversely impacts student retention. This book will stand as a single source to which instructors and students can go to obtain a comprehensive compendium of NMR problems of varying difficulty.

. Presents strategies for assigning resonances to known structures and for deducing structures of unknown organic molecules based on their NMR spectra
. Contains 30 known and 30 unknown structure determination problems
. Features a supporting website from which instructors can download the structures of the unknowns in selected chapters, digital versions of all figures, and raw data sets for processing

✦ Table of Contents

Content:
Front Matter, Page iii
Copyright, Page iv
Dedicated to, Page v
Preface, Pages xiii-xiv
Preface to the First Edition, Pages xv-xvi
Chapter 1 - Introduction, Pages 1-20
Chapter 2 - Instrumental Considerations, Pages 21-57
Chapter 3 - Data Collection, Processing, and Plotting, Pages 59-100
Chapter 4 - ¹H and ¹³C Chemical Shifts, Pages 101-112
Chapter 5 - Symmetry and Topicity, Pages 113-121
Chapter 6 - Through-Bond Effects: Spin-Spin (J) Coupling, Pages 123-168
Chapter 7 - Through-Space Effects: The Nuclear Overhauser Effect (NOE), Pages 169-184
Chapter 8 - Molecular Dynamics, Pages 185-197
Chapter 9 - Strategies for Assigning Resonances to Atoms within a Molecule, Pages 199-221
Chapter 10 - Strategies for Elucidating Unknown Molecular Structures, Pages 223-236
Chapter 11 - Simple Assignment Problems, Pages 237-287
Chapter 12 - Complex Assignment Problems, Pages 289-340
Chapter 13 - Simple Unknown Problems, Pages 341-378
Chapter 14 - Complex Unknown Problems, Pages 379-426
Chapter 15 - More Assignment Problems, Pages 427-477
Chapter 16 - More Unknown Problems, Pages 479-525
Glossary of Terms, Pages 527-555
Index, Pages 557-574