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Organic Protein Chemistry: Drug Discovery Through the Chemical Modification of Proteins

✍ Scribed by Joerg Rademann

Publisher
John Wiley and Sons
Year
2004
Weight
7 KB
Volume
35
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

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## Abstract Proteins have inherent flexibility, and this plays a critical role in a vast array of biological functions, including ligand binding. Structure‐based drug design (SBDD) strategies incorporate biomolecular structures with computational methods to predict and optimize ligand–receptor comp