The actin cytoskeleton is an intracellular structure, which is involved in the onset and control of cell shape and function. In order for this relevant network to control its own and thus cell volume, specific interactions between the actin cytoskeleton and ion channel regulation controlling intrace
Organic osmolyte channels in cell volume regulation in vertebrates
β Scribed by Perlman, Deborah F.; Goldstein, Leon
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 105 KB
- Volume
- 283
- Category
- Article
- ISSN
- 0022-104X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Hypotonic swelling of isolated skate hepatocytes activates a regulatory volume decrease (RVD) which is achieved in part by the release of taurine and other intracellular organic osmolytes. Volume-activated taurine efflux appears to be mediated by an anion channel that exhibits a taurine/chloride per
Volume expansion of erythrocytes of little skate, Raja erinacea, triggers the opening of an osmolyte channel. We review this transport mechanism and further investigate the channel's physicochemical nature by probing the channel with a series of pyridoxine derivatives in skate RBC as well as in epit
Compatible organic osmolytes, such as betaine and taurine are involved in the regulation of Kupffer cell (KC) function, but nothing is known about osmolytes in liver endothelial cells. This was investigated here by studying the effect of aniso-osmotic exposure of rat liver sinusoidal endothelial cel
A variety of cells, including skate RBC, release osmolytes (e.g. taurine) when hypotonically swollen as part of a regulatory volume decrease. In this study we show that skate RBC also release ATP into the incubation medium under the same conditions. Furthermore extracellular ATP as well as other nuc
## Abstract GLYT1, a glycine transporter belonging to the neurotransmitter transporter family, has recently been identified as a novel cell volumeβregulatory mechanism in the earliest stages of the mouse preimplantation embryo. It apparently acts by regulating the steadyβstate intracellular concent