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Organ variation in the mutagenicity of MeIQ in Big Blue® lacI transgenic mice

✍ Scribed by Takayoshi Suzuki; Makoto Hayashi; Masako Ochiai; Keiji Wakabayashi; Toshikazu Ushijima; Takashi Sugimura; Minako Nagao; Toshio Sofuni

Book ID
117331666
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
320 KB
Volume
369
Category
Article
ISSN
0165-1218

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✍ T. Suzuki; T. Itoh; M. Hayashi; Y. Nishikawa; S. Ikezaki; F. Furukawa; M. Takaha 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 482 KB 👁 2 views

Organ specificity in the lac/ mutant frequency (MF) induced by dimethylnitrosamine (DMN) was analyzed in lung, liver, kidney, bone marrow, urinary bladder, and testis of Big Blue@ mice. Cell proliferative activity was also analyzed in some of these tissues by immunohistochemical staining of prolifer