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Organ-specific susceptibility of p53 knockout mice to N-bis(2-hydroxypropyl)nitrosamine carcinogenesis

โœ Scribed by Akihiro Hirata; Tetsuya Tsukamoto; Masami Yamamoto; Hiroki Sakai; Tokuma Yanai; Toshiaki Masegi; Lawrence A. Donehower; Masae Tatematsu


Book ID
116333904
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
495 KB
Volume
238
Category
Article
ISSN
0304-3835

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## Abstract Deregulated proliferation is one of the fundamental characteristics of carcinogenesis. p27 is one of the most well characterized negative cell cycle regulator. In our previous study, expression of p27 protein was found to be dramatically suppressed on stimulation of cell proliferation b