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Organ Levels of Amitriptyline and Nortriptyline in Fatal Amitriptyline Poisoning

✍ Scribed by Kristinsson, J. ;Jóhannesson, T. ;Bjarnason, O. ;Geirsson, G.

Book ID
114800237
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
151 KB
Volume
52
Category
Article
ISSN
0001-6683

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✍ J. E. Burch 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 506 KB

Five elderly depressed patients were treated with amitriptyline (AT) and nortriptyline (NT) in turn, in a crossover design. Steady-state plasma drug levels were compared with those calculated for eight healthy subjects of previous single-dose studies. Plasma clearances were on average about 2.5 time