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Orexin-A excites pyramidal neurons in layer 2/3 of the rat prefrontal cortex

✍ Scribed by Jie Yan; Chao He; Jian-Xia Xia; Dan Zhang; Zhi-An Hu

Book ID: 116774198
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 533 KB
Volume: 520
Category: Article
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2012.05.038

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## Abstract Hypocretins are crucial for the regulation of wakefulness by the excitatory actions on multiple subcortical arousal systems. To date, there is little information about the direct postsynaptic excitatory effects of hypocretins on the neurons in prefrontal cortex (PFC), which is important