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Orally disintegrating olanzapine and potential differences in treatment-emergent weight gain

✍ Scribed by Jamie Karagianis; Vicki Poole Hoffmann; Belen Arranz; Tamás Treuer; Gerald A. Maguire; Lieuwe de Haan; Bharat Chawla

Book ID
102266673
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
135 KB
Volume
23
Category
Article
ISSN
0885-6222

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✦ Synopsis

Abstract

Several papers and communications have reported possible weight reduction or less weight gain when patients start or switch to orally disintegrating olanzapine, as contrasted with standard oral olanzapine tablets. In this paper, the current literature is reviewed and hypothesized mechanisms of action are discussed. The data are still preliminary and mechanisms of action are not well understood. Randomized controlled trials are needed to further evaluate change in weight during treatment with orally disintegrating olanzapine. Copyright © 2008 John Wiley & Sons, Ltd.

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