The [ 4C] labelled synthesis of two benzisothiazolone based inhibitors of Human Leukocyte Elastase is described. These are The synthesis of the intermediate [3-14C]-2-(chloromethyl)-6-methoxy-4-( l-methylethyl)-l,2benzisothiazol-3(2H)-one 1 ,I-dioxide, 8, common to both these syntheses. was achieve
โฆ LIBER โฆ
Orally Bioavailable Benzisothiazolone Inhibitors of Human Leukocyte Elastase
โ Scribed by Hlasta, Dennis J.; Subramanyam, Chakrapani; Bell, Malcolm R.; Carabateas, Philip M.; Court, John J.; Desai, Ranjit C.; Drozd, Marion L.; Eickhoff, W. Mark; Ferguson, Edward W.; Gordon, Robert J.; Dunlap, Richard P.; Franke, Catherine A.; Mura, Albert J.; Rowlands, Anne; Johnson, Judith A.; Kumar, Virendra; Maycock, Alan L.; Mueller, Karl R.; Pagani, Edward D.; Robinson, David T.; Saindane, Manohar T.; Silver, Paul J.; Subramanian, Sandhya
- Book ID
- 127002541
- Publisher
- American Chemical Society
- Year
- 1995
- Tongue
- English
- Weight
- 752 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0022-2623
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