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Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse

✍ Scribed by F. Calcinaro; S. Dionisi; M. Marinaro; P. Candeloro; V. Bonato; S. Marzotti; R. B. Corneli; E. Ferretti; A. Gulino; F. Grasso; C. De Simone; U. Di Mario; A. Falorni; M. Boirivant; F. Dotta

Publisher: Springer
Year: 2005
Tongue: English
Weight: 446 KB
Volume: 48
Category: Article
ISSN: 0012-186X
DOI: 10.1007/s00125-005-1831-2

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## and Research Laboratories of the Behringwerkee, Marburg We have evaluated the effects of a treatment with soluble interleukin-1 receptor (sIL-1R) in the accelerated model of autoimmune diabetes induced by cyclophosphamide (CY) in the non-obese diabetic (NOD) mouse. Prior to the CY challenge (35