Oral immunization with different assembly forms of the HPV 16 major capsid protein L1 induces neutralizing antibodies and cytotoxic T-lymphocytes

Parenteral and oral immunization with a

Parenteral and oral immunization with a plasmid DNA expressing the human papillomavirus 16-L1 gene induces systemic and mucosal antibodies and cytotoxic T lymphocyte responses

✍ Leticia Rocha-Zavaleta; Jorge E. Alejandre; Alejandro Garcia-Carranca 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 374 KB

## Abstract The association of human papillomavirus (HPV) infection and cervical cancer has been demonstrated. The development of a prophylactic vaccine to protect against primary HPV infection may therefore be an efficient means to reduce the incidence of this cancer worldwide. To assess the capac