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Oral dosage forms with a core and shell with the same polymer containing different drug concentrations

✍ Scribed by E.M. Ouriemchi; J. Bouzon; J.M. Vergnaud


Book ID
113366615
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
679 KB
Volume
102
Category
Article
ISSN
0378-5173

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The applicability of a polymer-drug interacted system in the physicochemical design of pharmaceutical dosage forms has been investigated. Salts of poly(methy1 vinyl ether/maleic anhydride) and methapyrilene base were prepared. In vitro release patterns were determined by an equilibrium dialysis proc