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Oral delivery of proteins by biodegradable nanoparticles

โœ Scribed by Bakhru, Sasha H.; Furtado, Stacia; Morello, A. Peter; Mathiowitz, Edith

Book ID
120377662
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
659 KB
Volume
65
Category
Article
ISSN
0169-409X

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Biodegradable nanoparticles containing protein-fatty acid complexes for oral delivery of salmon calcitonin
โœ Hyuk Sang Yoo; Tae Gwan Park ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 179 KB

Biodegradable nanoparticles containing salmon calcitonin (sCT) were formulated using protein-fatty acid complexes, and their in vitro transport against a Caco-2 cell monolayer and the extent of in vivo oral uptake were assessed. Positively charged sCT was hydrophobically ion paired to form physical