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Oral delivery of insulin associated to polymeric nanoparticles in diabetic rats

✍ Scribed by Christiane Damgé; Philippe Maincent; Nathalie Ubrich

Book ID
113691432
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
504 KB
Volume
117
Category
Article
ISSN
0168-3659

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Poly(ε-caprolactone)/eudragit nanoparticles for oral delivery of aspart-insulin in the treatment of diabetes
✍ Christiane Damgé; Marie Socha; Nathalie Ubrich; Philippe Maincent 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 261 KB

Nanoparticles prepared with a blend of a biodegradable polyester (poly(epsilon-caprolactone)) and a polycationic nonbiodegradable acrylic polymer (Eudragit RS) have been used as a drug carrier for oral administration of a short-acting insulin analogue, aspart-insulin. Insulin-loaded nanoparticles, a