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Oral Delivery of a Renin Inhibitor Compound Using Emulsion Formulations

โœ Scribed by Tugrul T. Kararli; Thomas E. Needham; Marty Griffin; Grant Schoenhard; Leonard J. Ferro; Lisa Alcorn


Book ID
110343423
Publisher
Springer US
Year
1992
Tongue
English
Weight
951 KB
Volume
09
Category
Article
ISSN
0724-8741

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The objective of this study was to evaluate the pharmacokinetics of paclitaxel in a novel self-microemulsifying drug delivery system (SMEDDS) for improved oral administration with or without P-glycoprotein (P-gp) inhibitors. Methods. Paclitaxel SMEDDS formulation was optimized, in terms of droplet s