Varicella-zoster virus (VZV) was isolated from 29 samples of the vesicular fluid in 13 otherwise healthy children with varicella who were aged from 7 months to 7 years. Human embryonic lung cells were used for viral isolation, and VZV was identified by a characteristic cytopathic effect and an indir
Oral BVDU treatment of varicella and zoster in children with cancer
β Scribed by Y. Benoit; G. Laureys; M. -J. Delbeke; E. Clercq
- Book ID
- 104775638
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 536 KB
- Volume
- 143
- Category
- Article
- ISSN
- 0340-6997
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β¦ Synopsis
In the period June 1980-April 1983, 21 children with malignant disease were admitted because of an intercurrent varicella or zoster infection. They were treated with the new antiviral drug BVDU [(E)-5-(2-bromovinyl)-2'deoxyuridine]. The drug was administered orally at a dose of 15mg/kg per day for 5 days. All our patients responded promptly to BVDU treatment and recovered completely from their varicella or zoster infections without complications. No toxic side-effects due to the drug were observed.
π SIMILAR VOLUMES
## Abstract The nested polymerase chain reaction was used to detect varicella zoster virus (VZV) DNA in 67 samples of peripheral blood mononuclear cells (PBMC) from 39 otherwise healthy children with varicella. Eleven were during the incubation period and 56 were after appearance of rash. VZV DNA w
## Abstract The general use of the varicella vaccine requires the surveillance of varicellaβzoster virus (VZV) strains in patients infected with VZV. This paper reports the data achieved from a prospective study of genotyping VZV in Germany, analyzing the restriction fragment length polymorphism (R